Article

Impact of rare structural variant events in newly diagnosed multiple myeloma

2023-01-03

Abstract excerpt

<h4>ABSTRACT</h4> Whole genome sequencing (WGS) of newly diagnosed multiple myeloma patients (NDMM) has shown recurrent structural variant (SV) involvement in distinct regions of the genome (i.e. hotspots) and causing recurrent copy number alterations. Together with canonical immunoglobulin translocations, these SVs are recognized as “recurrent SVs”. More than half SVs were not involved in recurrent events. The s...

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Literature Corpus work: 3aabb1ad-d029-5c82-b7df-da6b6f0d3bdf
DOI: 10.1101/2023.01.03.522573

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