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Article

Klotho KL-VS haplotype does not improve cognition in a population-based sample of adults age 55-87 years.

Scientific reports - 5 Jul 2021

Müller Bernhard W, Hinney Anke, Scherbaum Norbert, Weimar Christian, Kleinschnitz Christoph, Peters Triinu, Hochfeld Lara, Pechlivanis Sonali, Stang Andreas, Jokisch Martha, Kowall Bernd

Abstract excerpt

The heterozygous human Klotho KL-VS haplotype has been associated with improved cognitive performance but results are inconsistent. Here we assessed Klotho KL-VS haplotype and cognition using data from the third examination of the population-based Heinz Nixdorf Recall Study. We analyzed cognition tests (immediate and delayed word list, Trail-Making Test [TMT] part A and B, Maze test, interference condition of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34226614
DOI: 10.1038/s41598-021-93211-x
PMCID: PMC8257625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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