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Article

The longevity gene Klotho is differentially associated with cognition in subtypes of schizophrenia.

Schizophrenia research - 1 Mar 2018

Morar Bharti, Badcock Johanna C, Phillips Michael, Almeida Osvaldo P, Jablensky Assen

Abstract excerpt

Cognitive impairment is a core feature of schizophrenia and impacts negatively the functioning of affected individuals. Cognitive decline correlates with aging, and is the primary cause of loss of independence and reduced quality of life. The klotho gene is a key modulator of aging, with expression deficiency resulting in premature aging, while overexpression extends lifespan and enhances cognition. A haplotype...

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Identifiers

PMID: 28673754
DOI: 10.1016/j.schres.2017.06.054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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The longevity gene Klotho is differentially associated with cognition in subtypes of schizophrenia.PMID 28673754Read ↗

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