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The Role of Ageing and Parenchymal Senescence on Macrophage Function and Fibrosis

17 Jun 2021

Abstract excerpt

In this review, we examine senescent cells and the overlap between the direct biological impact of senescence and the indirect impact senescence has via its effects on other cell types, particularly the macrophage. The canonical roles of macrophages in cell clearance and in other physiological functions are discussed with reference to their functions in diseases of the kidney and other organs. We also explore the...

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PMID: 34220864
DOI: 10.3389/fimmu.2021.700790

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