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Article

Cellular senescence: all roads lead to mitochondria.

The FEBS journal - 1 Mar 2023

Martini Hélène, Passos João F

Abstract excerpt

Senescence is a multi-functional cell fate, characterized by an irreversible cell-cycle arrest and a pro-inflammatory phenotype, commonly known as the senescence-associated secretory phenotype (SASP). Emerging evidence indicates that accumulation of senescent cells in multiple tissues drives tissue dysfunction and several age-related conditions. This has spurred the academic community and industry to identify new...

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Identifiers

PMID: 35048548
DOI: 10.1111/febs.16361
PMCID: PMC9296701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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