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Article

FBXW7 polymorphism asserts susceptibility to colorectal cancer.

Gene - 5 Apr 2024

Uroog Laraib, Zeya Bushra, Imtiyaz Khalid, Ahmad Wani Rauf, Moshahid Alam Rizvi M

Abstract excerpt

FBXW7, belonging to the F-Box protein family, is considered a candidate cancer susceptibility gene. Our findings indicate that single nucleotide polymorphisms (SNPs) in the FBXW7 gene are linked to cancer risk, strengthening FBXW7's role in the pathogenesis of colorectal cancer. Our case-control study comprised of 450 patients diagnosed with colorectal cancer (CRC) and an equal number of 450 healthy subjects....

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PMID: 38244948
DOI: 10.1016/j.gene.2024.148181

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