Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FBXW7 and Its Downstream NOTCH Pathway Could be Potential Indicators of Organ-Free Metastasis in Colorectal Cancer

27 May 2022

Abstract excerpt

Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths globally. Metastasis is associated with a poor prognosis, yet the underlying molecular mechanism(s) remained largely unknown. In this study, a total of 85 CRC patients were included and the primary tumor lesions were evaluated by next-generation sequencing using a targeted panel for genetic aberrations. Patients were sub-divided...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer-related Molecular Pathways
Share to Cholangiocarcinoma and Gallbladder Cancer Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35712679
DOI: 10.3389/fonc.2021.783564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FBXW7 and Its Downstream NOTCH Pathway Could be Potential Indicators of Organ-Free Metastasis in Colorectal CancerPMID 35712679Read ↗

Clinical Significance of Fbxw7 Tumor Suppressor Gene Mutations and Expression in Human Colorectal Cancer: A Systemic Review and Meta-analysisSemantic proximity Read ↗

Alteration of FBXW7 is Associated with Worse Survival in Patients Undergoing Resection of Colorectal Liver Metastases.Semantic proximity Read ↗

Clinical significance of FBXW7 tumor suppressor gene mutations and expression in human colorectal cancer: a systemic review and meta-analysis.Semantic proximity Read ↗

Prognostic value of FBXW7 tumor suppressor gene expression and mutations in patients with colorectal cancer: A meta-analysis.Semantic proximity Read ↗

Comprehensive characterization of FBXW7 mutational and clinicopathological profiles in human colorectal cancersSemantic proximity Read ↗

Characterization of genomic alterations in Chinese colorectal cancer patients with liver metastases.Semantic proximity Read ↗

The mechanism investigation of mutation genes in liver and lung metastasis of colorectal cancer by using NGS technique.Semantic proximity Read ↗

Molecular dissection of CRC primary tumors and their matched liver metastases reveals critical role of immune microenvironment, EMT and angiogenesis in cancer metastasis.Semantic proximity Read ↗

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.Semantic proximity Read ↗

Multi-Omics Analysis of the Tumor Microenvironment in Liver Metastasis of Colorectal Cancer Identified FJX1 as a Novel BiomarkerSemantic proximity Read ↗

Characterization of Genomic Alterations in Colorectal Liver Metastasis and Their Prognostic ValueSemantic proximity Read ↗

Uncovering the Regulatory Role of Long Non-Coding RNAs in Colorectal Cancer Progression and Liver Metastasis: Implications for Therapeutic and Diagnostic TargetingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.