Article
FBXW7 mutation analysis and its correlation with clinicopathological features and prognosis in colorectal cancer patients.
The International journal of biological markers - 24 Feb 2015
Chang Chia-Chu, Lin Hung-Hsin, Lin Jen-Kou, Lin Chun-Chi, Lan Yuan-Tzu, Wang Huann-Sheng, Yang Shung-Haur, Chen Wei-Shone, Lin Tzu-Chen, Jiang Jeng-Kai, Chang Shih-Ching
Abstract excerpt
PURPOSE: This study aimed to determine the prognostic value of mutations in the tumor suppressor gene FBXW7 for clinical outcomes in colorectal cancer (CRC). METHODS: Between January 2000 and December 2009, FBXW7 mutations in tumor tissues from 1,519 CRC patients at Taipei Veterans General Hospital were assessed using a MassArray system. We compared the clinicopathological variables and prognosis between the...
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