Article
Neutralizing Antibody Induction Associated with a Germline Immunoglobulin Gene Polymorphism in Neutralization-Resistant SIVsmE543-3 Infection.
Viruses - 21 Jun 2021
Nomura Yuto, Matsuoka Saori, Okazaki Midori, Kuwata Takeo, Matano Tetsuro, Ishii Hiroshi
Abstract excerpt
Antibody responses are crucial for the control of virus infection. Understanding of the mechanism of antibody induction is important for the development of a vaccine eliciting effective anti-virus antibodies. Virus-specific B cell receptor (BCR)/antibody repertoires are different among individuals, but determinants for this difference remain largely unclear. We have recently reported that a germline BCR...
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