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Article

Induction of antibody-mediated neutralization in SIVmac239 by a naturally acquired V3 mutation.

Virology - 25 Apr 2010

Faith Seth A, Wu Yingyun, Kuhrt David, Steckbeck Jonathan D, Craigo Jodi K, Clements Janice E, Cole Kelly Stefano

Abstract excerpt

Achieving humoral immunity against human immunodeficiency virus (HIV) is a major obstacle in AIDS vaccine development. Despite eliciting robust humoral responses to HIV, exposed hosts rarely produce broadly neutralizing antibodies. The present study utilizes simian immunodeficiency virus (SIV) to identify viral epitopes that conferred antibody neutralization to clone SIV/17E-CL, an in vivo variant derived from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20153009
DOI: 10.1016/j.virol.2010.01.014
PMCID: PMC3351114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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