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Article

Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.

PLoS pathogens - 2 Sept 2010

Ozkaya Sahin Gülşen, Bowles Emma J, Parker Joe, Uchtenhagen Hannes, Sheik-Khalil Enas, Taylor Stephen, Pybus Oliver G, Mäkitalo Barbro, Walther-Jallow Lilian, Spångberg Mats, Thorstensson Rigmor, Achour Adnane, Fenyö Eva Maria, Stewart-Jones Guillaume B E, Spetz Anna-Lena

Abstract excerpt

Neutralizing antibodies (NAb) able to react to heterologous viruses are generated during natural HIV-1 infection in some individuals. Further knowledge is required in order to understand the factors contributing to induction of cross-reactive NAb responses. Here a well-established model of experimental pathogenic infection in cynomolgus macaques, which reproduces long-lasting HIV-1 infection, was used to study...

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Source

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Identifiers

PMID: 20824092
DOI: 10.1371/journal.ppat.1001084
PMCID: PMC2932721

Genes

PGD

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Source receipt: pubmed, retrieved 7 Sept 2026.

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