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Evaluation of Somatic Mutations in Solid Metastatic Pan-Cancer Patients

3 Jun 2021

Abstract excerpt

Metastasis continues to be the primary cause of all cancer-related deaths despite the recent advancements in cancer treatments. To evaluate the role of mutations in overall survival (OS) and treatment outcomes, we analyzed 957 metastatic patients with seven major cancer types who had available molecular testing results with a FoundationOne CDx® panel. The most prevalent genes with somatic mutations were TP53,...

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PMID: 34204917
DOI: 10.3390/cancers13112776

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