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Article

Targeting mutations in cancer.

The Journal of clinical investigation - 15 Apr 2022

Waarts Michael R, Stonestrom Aaron J, Park Young C, Levine Ross L

Abstract excerpt

Targeted therapies have come to play an increasingly important role in cancer therapy over the past two decades. This success has been made possible in large part by technological advances in sequencing, which have greatly advanced our understanding of the mutational landscape of human cancer and the genetic drivers present in individual tumors. We are rapidly discovering a growing number of mutations that occur...

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Identifiers

PMID: 35426374
DOI: 10.1172/JCI154943
PMCID: PMC9012285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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