Article
Pan-cancer whole genome comparison of primary and metastatic solid tumors
2022-06-17
Abstract excerpt
Metastatic cancer remains almost inevitably a lethal disease. A better understanding of disease progression and response to therapies therefore remains of utmost importance. Here, we characterize the genomic differences between early-stage untreated primary tumors and late-stage treated metastatic tumors using a harmonized pan-cancer (re-)analysis of 7,152 whole-genome-sequenced tumors. In general, our analysis sh...
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Identifiers and source
- Literature Corpus work
- ba3054d6-36b1-585d-84a4-089079867e23
- DOI
- 10.1101/2022.06.17.496528