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TP53 Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients

3 Feb 2021

Abstract excerpt

Molecular profiling with next generation sequencing (NGS) delivers key information on mutant gene sequences, copy number alterations, gene-fusions, and with immunohistochemistry (IHC), is a valuable tool in clinical decision making for patients entering investigational agent trials. Our objective was to elucidate mutational profiles from primary versus metastatic sites from advanced cancer patients to guide...

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PMID: 33546249
DOI: 10.3390/cancers13040597

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