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Article

Reversal of behavioural phenotype by the cannabinoid-like compound VSN16R in fragile X syndrome mice.

Brain : a journal of neurology - 29 Mar 2022

Hurley Michael J, Deacon Robert M J, Chan A W Edith, Baker David, Selwood David L, Cogram Patricia

Abstract excerpt

Fragile X syndrome is the most common inherited intellectual disability and mono-genetic cause of autism spectrum disorder. It is a neurodevelopmental condition occurring due to a CGG trinucleotide expansion in the FMR1 gene. Polymorphisms and variants in large-conductance calcium-activated potassium channels are increasingly linked to intellectual disability and loss of FMR protein causes reduced...

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Identifiers

PMID: 34196695
DOI: 10.1093/brain/awab246
PMCID: PMC8967084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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