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Role of the endocannabinoid system in fragile X syndrome: potential mechanisms for benefit from cannabidiol treatment

9 Jan 2023

Abstract excerpt

Abstract Multiple lines of evidence suggest a central role for the endocannabinoid system (ECS) in the neuronal development and cognitive function and in the pathogenesis of fragile X syndrome (FXS). This review describes the ECS, its role in the central nervous system, how it is dysregulated in FXS, and the potential role of cannabidiol as a treatment for FXS. FXS is caused by deficiency or absence of the...

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PMID: 36624400
DOI: 10.1186/s11689-023-09475-z

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