Article

Vorinostat corrects cognitive and non-cognitive symptoms in a mouse model of fragile X syndrome

2020-08-06

Abstract excerpt

<h4>ABSTRACT</h4> Fragile X syndrome (FXS) is caused by mutations in the FMR1 (fragile X mental retardation 1) gene. It is a significant form of heritable intellectual disability with comorbidity of other symptoms such as autism. Due to the lack of efficacious medication, repurposing the existing FDA-approved drugs may offer an opportunity to advance clinical intervention for FXS. Analysis of the whole-genome tr...

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Literature Corpus work: a50d2207-70d4-5fdb-93f5-5e909a968bb3
DOI: 10.1101/2020.08.05.238568

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