Article

Cannabidiol-Induced Recovery of Social Behaviour in Mouse Models of Syndromic Autism

2025-12-17

Abstract excerpt

<title>Abstract</title> <p> Despite the growing prevalence of autism, no pharmacological interventions have been approved for core symptoms. The endocannabinoid system (ECS) has recently gained interest as a potential target for treating autism. Cannabidiol (CBD), a compound found in <italic>Cannabis sativa</italic> , is a potential treatment due to its tolerability and promising early results in fragile X syn...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ad833e9d-106a-5000-956e-dcbcb41a9c08
DOI: 10.21203/rs.3.rs-6683632/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cannabidiol-Induced Recovery of Social Behaviour in Mouse Models of Syndromic AutismDOI 10.21203/rs.3.rs-6683632/v2Read

Cannabidiol-Induced Recovery of Social Behaviour in Mouse Models of Syndromic AutismSemantic proximity Read

Pharmacological inhibition of the primary endocannabinoid producing enzyme, DGL-α, induces autism spectrum disorder-like and co-morbid phenotypes in adult C57BL/J mice.Semantic proximity Read

Targeting synaptic plasticity and acetylcholine dysregulation in the medial prefrontal cortex: Rosmarinic acid attenuates Autism-like phenotypes in Shank3B-/- mice via the CREB/BDNF pathway.Semantic proximity Read

The role of the endocannabinoid system in autism spectrum disorders: Evidence from mouse studies.Semantic proximity Read

Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams-Beuren syndrome.Semantic proximity Read

Cannabinoids for People with ASD: A Systematic Review of Published and Ongoing StudiesSemantic proximity Read

Behavioral profiles of mouse models for autism spectrum disorders.Semantic proximity Read

Anandamide and 2-arachidonoylglycerol differentially modulate autistic-like traits in a genetic model of autism based on FMR1 deletion in rats.Semantic proximity Read

Cannabidiol, but Not Δ9-Tetrahydrocannabinol, Has Strain- and Genotype-Specific Effects in Models of Psychosis.Semantic proximity Read

Prenatal Cannabidiol and THC Exposure Induce Sex-Specific Executive Dysfunction via Divergent Pathological Rewiring of the Adult Medial Prefrontal CortexSemantic proximity Read

Juvenile Shank3b deficient mice present with behavioral phenotype relevant to autism spectrum disorder.Semantic proximity Read

Endocannabinoid markers in autism spectrum disorder: A scoping review of human studies.Semantic proximity Read