Article
No association between the Trp53 codon 72 polymorphism and head and neck cancer: a case-control study in a South Indian population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2010
Suresh K, Chandirasekar R, Kumar B Lakshman, Venkatesan R, Sasikala K
Abstract excerpt
Genetic polymorphisms are important for predispositions to several human cancers. In the tumour suppressor Trp53 gene, a codon 72 polymorphism is frequent in the form of a single nucleotide polymorphism that leads to substitution of an arginine for a proline. In the present study, we analysed the association of Trp53 codon 72 polymorphs with head and neck cancer through a case-control study approach with PCR-RFLP...
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