Article
p53 exon 4 (codon 72) polymorphism and exon 7 (codon 249) mutation in breast cancer patients in southern region (Madurai) of Tamil Nadu.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Vijayaraman Kiruthiga Perumal, Veluchamy Mohanasundari, Murugesan Pravina, Shanmugiah Karutha Pandian, Kasi Pandima Devi
Abstract excerpt
BACKGROUND: We investigated the association between polymorphisms in the p53 tumor suppressor gene and breast cancer risk in women especially in the Southern part of India. METHODS: Genotyping was performed for 50 breast cancer women and 50 controls to determine the status of p53 exon 4 codon 72 polymorphism and exon 7 codon 249 mutation and their possible role in breast cancer risk. RESULTS: Frequency of Arg/Arg...
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