The p53 codon 72 (Arg72Pro) polymorphism is associated with the degree of insulin resistance in type 2 diabetic subjects: a cross-sectional study.

doi:10.1007/s00592-012-0450-x

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Article

The p53 codon 72 (Arg72Pro) polymorphism is associated with the degree of insulin resistance in type 2 diabetic subjects: a cross-sectional study.

Acta diabetologica - 1 Jun 2013

Bonfigli Anna Rita, Sirolla Cristina, Testa Roberto, Cucchi Michela, Spazzafumo Liana, Salvioli Stefano, Ceriello Antonio, Olivieri Fabiola, Festa Roberto, Procopio Antonio Domenico, Brandoni Gabriele, Boemi Massimo, Marra Maurizio, Franceschi Claudio

Abstract excerpt

Tumor suppressor protein p53 has been demonstrated to regulate genes involved in energy generating metabolic pathways and apoptosis. To date, a new field of research is the involvement of TP53 codon 72 (Arg72Pro) polymorphism in the diabetic disease. The aim of this study was to evaluate whether the genotype and the related genetic models of Arg72Pro polymorphism of TP53 (rs1042522) are associated with insulin...

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PMID: 23269546
DOI: 10.1007/s00592-012-0450-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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