Article
Genetic susceptibility.
Clinics in chest medicine - 1 Mar 2014
Marciniak Stefan J, Lomas David A
Abstract excerpt
Why only 20% of smokers develop clinically relevant chronic obstructive pulmonary disease (COPD) was a puzzle for many years. Now, epidemiologic studies point clearly toward a large heritable component. The combination of genome-wide association studies and candidate gene analysis is helping to identify those genetic variants responsible for an individual's susceptibility to developing COPD. In this review, the...
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