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Article

Prmt5 promotes vascular morphogenesis independently of its methyltransferase activity.

PLoS genetics - 1 Jun 2021

Quillien Aurélie, Gilbert Guerric, Boulet Manon, Ethuin Séverine, Waltzer Lucas, Vandel Laurence

Abstract excerpt

During development, the vertebrate vasculature undergoes major growth and remodeling. While the transcriptional cascade underlying blood vessel formation starts to be better characterized, little is known concerning the role and mode of action of epigenetic enzymes during this process. Here, we explored the role of the Protein Arginine Methyl Transferase Prmt5 in blood vessel formation as well as hematopoiesis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34153034
DOI: 10.1371/journal.pgen.1009641
PMCID: PMC8248709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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