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Article

Population modification strategies for malaria vector control are uniquely resilient to observed levels of gene drive resistance alleles.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Aug 2021

Lanzaro Gregory C, Sánchez C Hector M, Collier Travis C, Marshall John M, James Anthony A

Abstract excerpt

Cas9/guide RNA (gRNA)-based gene drive systems are expected to play a transformative role in malaria elimination efforts., whether through population modification, in which the drive system contains parasite-refractory genes, or population suppression, in which the drive system induces a severe fitness load resulting in population decline or extinction. DNA sequence polymorphisms representing alternate alleles at...

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PMID: 34151435
DOI: 10.1002/bies.202000282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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