Factors that regulate expression patterns of insulin-like peptides and their association with physiological and metabolic traits in Drosophila.

doi:10.1016/j.ibmb.2021.103609

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Factors that regulate expression patterns of insulin-like peptides and their association with physiological and metabolic traits in Drosophila.

Insect biochemistry and molecular biology - 1 Aug 2021

Semaniuk Uliana, Strilbytska Olha, Malinovska Karina, Storey Kenneth B, Vaiserman Alexander, Lushchak Volodymyr, Lushchak Oleh

Abstract excerpt

Insulin-like peptides (ILPs) and components of the insulin signaling pathway are conserved across different animal phyla. Eight ILPs (called DILPs) and two receptors, dInR and Lgr3, have been described in Drosophila. DILPs regulate varied physiological traits including lifespan, reproduction, development, feeding behavior, stress resistance and metabolism. At the same time, different conditions such as nutrition,...

Topics

Animals
Drosophila Proteins
Drosophila melanogaster
Feeding Behavior
Gene Expression Regulation
Insulin
Intercellular Signaling Peptides and Proteins
Longevity
Mutation
Phenotype
RNA, Messenger
Receptor Protein-Tyrosine Kinases

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reproduction

Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 34146686
DOI: 10.1016/j.ibmb.2021.103609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.