Article
Drosophila adiponectin receptor in insulin producing cells regulates glucose and lipid metabolism by controlling insulin secretion.
PloS one - 1 Jan 2013
Kwak Su-Jin, Hong Seung-Hyun, Bajracharya Rijan, Yang Se-Yeol, Lee Kyu-Sun, Yu Kweon
Abstract excerpt
Adipokines secreted from adipose tissue are key regulators of metabolism in animals. Adiponectin, one of the adipokines, modulates pancreatic beta cell function to maintain energy homeostasis. Recently, significant conservation between Drosophila melanogaster and mammalian metabolism has been discovered. Drosophila insulin like peptides (Dilps) regulate energy metabolism similarly to mammalian insulin. However,...
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