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Article

Age related changes in microglial phenotype vary between CNS regions: grey versus white matter differences.

Brain, behavior, and immunity - 1 Jul 2012

Hart Adam D, Wyttenbach Andreas, Perry V Hugh, Teeling Jessica L

Abstract excerpt

Subtle regional differences in microglial phenotype exist in the adult mouse brain. We investigated whether these differences were amplified during ageing and following systemic challenge with lipopolysaccharide (LPS). We studied microglial morphology and phenotype in young (4mo) and aged (21mo) C57/BL6 mice using immunohistochemistry and quantified the expression levels of surface molecules on microglia in white...

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Identifiers

PMID: 22155499
DOI: 10.1016/j.bbi.2011.11.006
PMCID: PMC3381227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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