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Signatures of B Cell Receptor Repertoire Following Pneumocystis Infection

31 May 2021

Abstract excerpt

B cells play vital roles in host defense against Pneumocystis infection. However, the features of the B cell receptor (BCR) repertoire in disease progression remain unclear. Here, we integrated single-cell RNA sequencing and single-cell BCR sequencing of immune cells from mouse lungs in an uninfected state and 1–4 weeks post-infection in order to illustrate the dynamic nature of B cell responses during...

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PMID: 34135870
DOI: 10.3389/fmicb.2021.636250

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