Article

Profiling immunoglobulin repertoires across multiple human tissues by RNA Sequencing

2016-11-22

Abstract excerpt

Assay-based approaches provide a detailed view of the adaptive immune system by profiling immunoglobulin (Ig) receptor repertoires. However, these methods carry a high cost and lack the scale of standard RNA sequencing (RNA-Seq). Here we report the development of ImReP, a novel computational method for rapid and accurate profiling of the immunoglobulin repertoire from regular RNA-Seq data. ImReP can also accuratel...

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Literature Corpus work: e1436bb7-46f6-51a0-8ab0-c7c0c29b44e6
DOI: 10.1101/089235

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