Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-Cell TCR Sequencing Reveals the Dynamics of T Cell Repertoire Profiling During Pneumocystis Infection

20 Apr 2021

Abstract excerpt

T cell responses play critical roles in host adaptive immunity against Pneumocystis. However, the dynamics and diversity of the T cell immune repertoire in human immunodeficiency virus (HIV)-negative Pneumocystis pneumonia (PCP) remains unclear. In this study, single-cell RNA and single-cell T cell receptor (TCR) sequencing were applied to cells sorted from lung tissues of mice infected with Pneumocystis. Our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunodeficiency and Autoimmune Disorders
Share to Pneumocystis jirovecii pneumonia detection and treatment
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33959105
DOI: 10.3389/fmicb.2021.637500

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-Cell TCR Sequencing Reveals the Dynamics of T Cell Repertoire Profiling During Pneumocystis InfectionPMID 33959105Read ↗

Peripheral immune phenotypes and T cell receptor repertoire in pneumocystis pneumonia in HIV-1 infected patients.Semantic proximity Read ↗

Signatures of B Cell Receptor Repertoire Following Pneumocystis InfectionSemantic proximity Read ↗

Single-Cell Transcriptomics Reveals Depletion and Dysregulation of Mycobacterium tuberculosis –Specific Th1 and Th17 Cells Early After Acquisition of Human Immunodeficiency VirusSemantic proximity Read ↗

T Cell Receptor Repertoire Analysis Reveals Signatures of T Cell Responses to Human Mycobacterium tuberculosisSemantic proximity Read ↗

Single‐Cell Sequencing Reveals Functional Alterations in TuberculosisSemantic proximity Read ↗

Single-cell sequencing of PBMC characterizes the transformation of T cell subsets in the inflammatory microenvironment of RA-ILDSemantic proximity Read ↗

Single-cell immune profiling reveals functional diversity of T cells in tuberculous pleural effusionSemantic proximity Read ↗

Landscape of Exhausted T Cells in Tuberculosis Revealed by Single-Cell SequencingSemantic proximity Read ↗

Dissecting the landscape of activated CMV-stimulated CD4+ T cells in human by linking single-cell RNA-seq with T-cell receptor sequencingSemantic proximity Read ↗

Dissecting the Landscape of Activated CMV-Stimulated CD4+ T Cells in Humans by Linking Single-Cell RNA-Seq With T-Cell Receptor SequencingSemantic proximity Read ↗

Targeted reconstruction of T cell receptor sequence from single cell RNA-sequencing links CDR3 length to T cell differentiation stateSemantic proximity Read ↗

Distinct phenotypes and repertoires of bronchoalveolar and airway mucosal T cells in health and allergic asthma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.