Article
Peripheral immune phenotypes and T cell receptor repertoire in pneumocystis pneumonia in HIV-1 infected patients.
Clinical immunology (Orlando, Fla.) - 1 Apr 2022
Qiao Luxin, Cui Xiao, Jia Lin, Gao Yuxue, Wang Wenjing, Wei Feili, Zhang Zhili, Chen Dexi, Ma Yingmin, Zhang Yulin
Abstract excerpt
BACKGROUND: The host immune response to pneumocystis pneumonia (PCP) involves interactions among immune cell subsets and cytokines. However, the definite pathogenesis and immunological influences of P. jirovecii have not been fully elucidated. METHODS: Mass cytometry and high-throughput sequencing of the T cell receptor (TCR) were used to profile the host immune response to human immunodeficiency virus-1 (HIV-1)...
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