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A pan-immune panorama of bacterial pneumonia revealed by a large-scale single-cell transcriptome atlas

5 Jan 2025

Abstract excerpt

Abstract Bacterial pneumonia is a significant public health burden, contributing to substantial morbidity, mortality, and healthcare costs. Current therapeutic strategies beyond antibiotics and adjuvant therapies are limited, highlighting the need for a deeper understanding of the disease pathogenesis. Here, we employed single-cell RNA sequencing of 444,146 bronchoalveolar lavage fluid cells (BALFs) from a large...

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PMID: 39757231
DOI: 10.1038/s41392-024-02093-8

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