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Article

Smoothened and ARL13B are critical in mouse for superior cerebellar peduncle targeting

16 Jun 2021

Abstract excerpt

Patients with the ciliopathy Joubert syndrome present with physical anomalies, intellectual disability, and a hindbrain malformation described as the "molar tooth sign" due to its appearance on an MRI. This radiological abnormality results from a combination of hypoplasia of the cerebellar vermis and inappropriate targeting of the white matter tracts of the superior cerebellar peduncles. ARL13B is a...

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PMID: 34132778
DOI: 10.1093/genetics/iyab084

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Smoothened and ARL13B are critical in mouse for superior cerebellar peduncle targetingPMID 34132778Read ↗

Smoothened and ARL13B are critical in mouse for superior cerebellar peduncle targetingSemantic proximity Read ↗

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