Article

Smoothened and ARL13B are critical in mouse for superior cerebellar peduncle targeting

2021-01-30

Abstract excerpt

Patients with the ciliopathy Joubert syndrome present with physical anomalies, intellectual disability, and a hindbrain malformation described as the “molar tooth sign” due to its appearance on an MRI. This radiological abnormality results from a combination of hypoplasia of the cerebellar vermis and inappropriate targeting of the white matter tracts of the superior cerebellar peduncles. ARL13B is a cilia-enriched...

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Literature Corpus work: 50811a2d-0263-5424-8d96-da94cd4b1980
DOI: 10.1101/2021.01.29.428892

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