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Article

In silico analysis of deleterious SNPs of human MTUS1 gene and their impacts on subsequent protein structure and function.

PloS one - 1 Jan 2021

Rozario Liza Teresa, Sharker Tanima, Nila Tasnin Akter

Abstract excerpt

The mitochondrial tumor suppressor 1 (MTUS1) gene acts as a crucial tumor suppressor by inhibiting growth and proliferation of eukaryotic cells including tumor cell lines. Down regulation of MTUS1 gene has been implicated in a wide range of cancers as well as various human diseases. Alteration through nsSNPs can potentially damage the structure and/or function of the protein. As characterization of functional...

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Identifiers

PMID: 34125870
DOI: 10.1371/journal.pone.0252932
PMCID: PMC8202925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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