Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Computational analysis for the determination of deleterious nsSNPs in human MTHFD1 gene.

Computational biology and chemistry - 1 Oct 2017

Desai Mansi, Chauhan J B

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are the most common genetic polymorphisms and play a major role in many inherited diseases. Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) is one of the enzymes involved in folate metabolism. In the present study, the functional and structural consequences of nsSNPs of human MTHFD1 gene was analyzed using various computational tools like SIFT, PolyPhen2, PANTHER,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to MTHFD1 gene
Share to Methylenetetrahydrofolate Dehydrogenase (NADP)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Minor Histocompatibility Antigens

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 28734179
DOI: 10.1016/j.compbiolchem.2017.07.001

Genes

MTHFD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Computational analysis for the determination of deleterious nsSNPs in human MTHFD1 gene.PMID 28734179Read ↗

Computational analysis for the determination of deleterious nsSNPs in human MTHFR gene.Semantic proximity Read ↗

Computational screening of pathogenic missense nsSNPs in heme oxygenase 1 (HMOX1) gene and their structural and functional consequences.Semantic proximity Read ↗

In silico analysis of Single Nucleotide Polymorphisms (SNPs) in human BRAF gene.Semantic proximity Read ↗

Mutation analysis of pathogenic non-synonymous single nucleotide polymorphisms (nsSNPs) in WFS1 gene through computational approaches.Semantic proximity Read ↗

Computational analysis of functional single nucleotide polymorphisms associated with SLC26A4 gene.Semantic proximity Read ↗

Applications of computational algorithm tools to identify functional SNPs.Semantic proximity Read ↗

Computational identification of pathogenic associated nsSNPs and its structural impact in UROD gene: a molecular dynamics approach.Semantic proximity Read ↗

Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in human DNA repair genes.Semantic proximity Read ↗

Prediction of deleterious non-synonymous SNPs of human MDC1 gene: an in silico approach.Semantic proximity Read ↗

In silico analysis of deleterious SNPs of human MTUS1 gene and their impacts on subsequent protein structure and function.Semantic proximity Read ↗

Approaches and resources for prediction of the effects of non-synonymous single nucleotide polymorphism on protein function and interactions.Semantic proximity Read ↗

In-Silico Methods for Investigating the Effect of Single Nucleotide Polymorphisms on the Structure and Function of Proteins: A ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.