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Article

In silico functional, structural and pathogenicity analysis of missense single nucleotide polymorphisms in human MCM6 gene.

Scientific reports - 21 May 2024

Kamal Md Mostafa, Mia Md Sohel, Faruque Md Omar, Rabby Md Golam, Islam Md Numan, Talukder Md Enamul Kabir, Wani Tanveer A, Rahman M Atikur, Hasan Md Mahmudul

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are one of the most common determinants and potential biomarkers of human disease pathogenesis. SNPs could alter amino acid residues, leading to the loss of structural and functional integrity of the encoded protein. In humans, members of the minichromosome maintenance (MCM) family play a vital role in cell proliferation and have a significant impact on tumorigenesis. Among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38773180
DOI: 10.1038/s41598-024-62299-2
PMCID: PMC11109216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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