Efficient representations of tumor diversity with paired DNA-RNA aberrations.

Abstract excerpt

Cancer cells display massive dysregulation of key regulatory pathways due to now well-catalogued mutations and other DNA-related aberrations. Moreover, enormous heterogeneity has been commonly observed in the identity, frequency and location of these aberrations across individuals with the same cancer type or subtype, and this variation naturally propagates to the transcriptome, resulting in myriad types of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Computational Biology
• Share to DNA, Neoplasm
• Share to Gene Regulatory Networks