Article

Efficient Representations of Tumor Diversity with Paired DNA-RNA Aberrations

2020-04-25

Abstract excerpt

Cancer cells display massive dysregulation of key regulatory pathways due to now well-catalogued mutations and other DNA-related aberrations. Moreover, enormous heterogeneity has been commonly observed in the identity, frequency and location of these aberrations across individuals with the same cancer type or subtype, and this variation naturally propagates to the transcriptome, resulting in myriad types of dysreg...

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Literature Corpus work: dd79faa0-86ce-5421-87e7-498e5c68ae2c
DOI: 10.1101/2020.04.24.060129

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