Article

Combinatorial Detection of Conserved Alteration Patterns for Identifying Cancer Subnetworks

2018-07-16

Abstract excerpt

<h4>Background</h4> Advances in large scale tumor sequencing have lead to an understanding that there are combinations of genomic and transcriptomic alterations speciflc to tumor types, shared across many patients. Unfortunately, computational identiflcation of functionally meaningful shared alteration patterns, impacting gene/protein interaction subnetworks, has proven to be challenging. <h4>Findings</h4> We in...

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Literature Corpus work: 305d4d97-0e32-5387-a775-191ab1c38b8e
DOI: 10.1101/369850

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