Article

Pan-cancer benchmarking reveals complementary copy number signatures with distinct multi-omic predictability

2026-07-21

Abstract excerpt

Copy number signatures provide compact representations of the processes that shape cancer genomes, but signatures derived with different feature encodings are often interpreted as if they were interchangeable. We established a matched-sample pan-cancer benchmark of three major copy number signature compendia, comparing their activity structure, cross-framework concordance, patient stratification, outcome associati...

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Literature Corpus work: 9916e3c7-5aaf-5907-a94d-d753b6ad7c39
DOI: 10.64898/2026.07.20.739333

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