Article

Intratumor Heterogeneity Through the Lens of Gene Regulatory Networks

2025-04-07

Abstract excerpt

Intratumor heterogeneity (ITH), the presence of heterogeneous genomic and transcriptomic populations in tumor and its implications for the cancer therapies has been one of the focal points of computational cancer biology in the past years. While ITH is well characterized at the genomic level, the regulatory wiring connecting clonal genotypes to transcriptional states remains largely unmapped. To understand whether...

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Literature Corpus work: ff1369bf-4887-50d6-8f1f-34da0eaea4d2
DOI: 10.1101/2025.04.01.646625

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