Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations in 3'UTRs of SMUG1 and NEIL2 genes modulate breast cancer risk, survival and therapy response.

Mutagenesis - 27 Aug 2021

Cumova Andrea, Vymetalkova Veronika, Opattova Alena, Bouskova Veronika, Pardini Barbara, Kopeckova Katerina, Kozevnikovova Renata, Lickova Katerina, Ambrus Miloslav, Vodickova Ludmila, Naccarati Alessio, Soucek Pavel, Vodicka Pavel

Abstract excerpt

Breast cancer (BC) is the most frequent malignancy in women accounting for approximately 2 million new cases worldwide annually. Several genetic, epigenetic and environmental factors are known to be involved in BC development and progression, including alterations in post-transcriptional gene regulation mediated by microRNAs (miRNAs). Single nucleotide polymorphisms (SNPs) located in miRNA binding sites (miRSNPs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Disease-Free Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-(Apurinic or Apyrimidinic Site) Lyase

Share to DNA Glycosylases

Share to DNA Repair

Share to MicroRNAs

Share to Uracil-DNA Glycosidase

Source

Identifiers

PMID: 34097065
DOI: 10.1093/mutage/geab017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations in 3'UTRs of SMUG1 and NEIL2 genes modulate breast cancer risk, survival and therapy response.PMID 34097065Read ↗

Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy.Semantic proximity Read ↗

Variation within 3'-UTRs of base excision repair genes and response to therapy in colorectal cancer patients: A potential modulation of microRNAs binding.Semantic proximity Read ↗

Genetic variations in tumor-suppressor miRNA-encoding genes and their target genes: focus on breast cancer development and possible therapeutic strategies.Semantic proximity Read ↗

BreVamiR3': A comprehensive database for breast cancer-associated genetic variations in miRNA and 3' UTR of their target genes.Semantic proximity Read ↗

LncRNA polymorphisms and breast cancer risk.Semantic proximity Read ↗

rs15869 at miRNA binding site in BRCA2 is associated with breast cancer susceptibility.Semantic proximity Read ↗

Polymorphism of lncRNAs in breast cancer: Meta-analysis shows no association with susceptibility.Semantic proximity Read ↗

Impact of IGF2BP2 genetic variants and expression levels with the progression of endometrial cancer.Semantic proximity Read ↗

NOTCH Single Nucleotide Polymorphisms in the Predisposition of Breast and Colorectal Cancers in Saudi Patients.Semantic proximity Read ↗

Five Common Functional Polymorphisms in microRNAs and Susceptibility to Breast Cancer: An Updated Meta-Analysis.Semantic proximity Read ↗

Association between single-nucleotide polymorphisms in miRNA and breast cancer risk: an updated review.Semantic proximity Read ↗

DNA repair genes hOGG1, XRCC1 and ERCC2 polymorphisms and their molecular mapping in breast cancer patients from India.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.