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Article

rs15869 at miRNA binding site in BRCA2 is associated with breast cancer susceptibility.

Medical oncology (Northwood, London, England) - 1 Dec 2016

Cao Jingjing, Luo Chenglin, Yan Rui, Peng Rui, Wang Kaijuan, Wang Peng, Ye Hua, Song Chunhua

Abstract excerpt

BRCA1 and BRCA2 mutations confer an increased lifetime risk of breast cancer; however, the associations of microRNA (miRNA) binding site single nucleotide polymorphisms (SNPs) in 3' untranslated region (3'-UTR) of BRCA1 and BRCA2 with breast cancer (BC) risk were rarely reported. In this case-control study (498 BC patients and 498 matched controls), three SNPs (rs8176318, rs12516 and rs15869) were selected in the...

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Share to 3' Untranslated Regions
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Identifiers

PMID: 27807724
DOI: 10.1007/s12032-016-0849-2

Genes

BRCA2
BRCA1

Provenance

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