Article
Impact of IGF2BP2 genetic variants and expression levels with the progression of endometrial cancer.
International journal of medical sciences - 1 Jan 2026
Kan Chieh-Yi, Sun Yi-Hung, Lee Chung-Yuan, Su Shih-Chi, Chang Cheng-Chang, Tang Chih-Hsin, Chu Hsiao-Ju, Wang Po-Hui, Yang Shun-Fa
Abstract excerpt
Endometrial cancer (EC) is the most common gynecological cancer among women in high-income countries, and its intricate etiology involves a composite of genetic factors. Insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2) targets distinct types of RNA species to orchestrate tumor cell metabolism, invasion, and metastasis. Nevertheless, the impact of IGF2BP2 gene polymorphisms on the development of EC...
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