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BreVamiR3': A comprehensive database for breast cancer-associated genetic variations in miRNA and 3' UTR of their target genes.

Computers in biology and medicine - 1 Mar 2025

Chhichholiya Yogita, Kumar Vicky, Hlawndo Lalnunmawia, Sangave Kshitij, Singh Sandeep, Munshi Anjana

Abstract excerpt

Breast cancer (BC) is a multifactorial disease where microRNA (miRNA)-mediated dysregulated gene expression plays a pivotal role in tumorigenesis, progression, and clinical outcomes. Genetic variation, particularly SNPs in miRNA sequences and the 3' untranslated regions (3'UTRs) of their target genes, can disrupt miRNA-mRNA interactions, leading to altered gene expression. Despite several existing databases...

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Share to 3' Untranslated Regions
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Genetic

Share to Databases, Nucleic Acid

Share to CCND1 gene

Share to Gene Expression Regulation, Neoplastic

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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 39740512
DOI: 10.1016/j.compbiomed.2024.109639

Genes

CCND1
ERBB2
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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