Article
NOTCH Single Nucleotide Polymorphisms in the Predisposition of Breast and Colorectal Cancers in Saudi Patients.
Pathology oncology research : POR - 1 Jan 2021
Alanazi Ibrahim O, Shaik Jilani Purusottapatnam, Parine Narasimha Reddy, Al Naeem Abdulrahman, Azzam Nahla A, Almadi Majid A, Aljebreen Abdulrahman M, Alharbi Othman, Alanazi Mohammad Saud, Khan Zahid
Abstract excerpt
Breast cancer (BC) is a heterogeneous disease and is one of the most common malignancy affecting women worldwide while colorectal cancer (CRC) is estimated to be the third common cancer and second leading cause of cancer related death globally. Both BC and CRC involve multiple genetic and epigenetic alterations in genes belonging to various signaling pathways including NOTCH that has been implicated in the...
Topics
- Biomarkers, Tumor
- Breast Neoplasms
- Case-Control Studies
- Colorectal Neoplasms
- Female
- Follow-Up Studies
- Genotype
- Humans
- Male
- Middle Aged