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Article

Association between single-nucleotide polymorphisms in miRNA and breast cancer risk: an updated review.

Biological research - 28 Aug 2021

Arancibia Trinidad, Morales-Pison Sebastian, Maldonado Edio, Jara Lilian

Abstract excerpt

Breast cancer (BC), a heterogeneous, aggressive illness with high mortality, is essentially a genomic disease. While the high-penetrance genes BRCA1 and BRCA2 play important roles in tumorigenesis, moderate- and low-penetrance genes are also involved. Single-nucleotide polymorphisms (SNPs) in microRNA (miRNA) genes have recently been identified as BC risk factors. miRNA genes are currently classified as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34454612
DOI: 10.1186/s40659-021-00349-z
PMCID: PMC8401249

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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