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Mitochondrial DNA polymorphisms and biogenesis genes in primary and metastatic uveal melanoma cell lines.

Cancer genetics - 1 Aug 2021

Singh Lata, Atilano Shari R, Jager Martine J, Kenney M Cristina

Abstract excerpt

PURPOSE: This study was designed to identify mitochondrial (mt) DNA variations in primary and metastatic uveal melanoma (UM) cell lines and their relation with cell metabolism to gain insight into metastatic progression. METHOD: The entire mtDNA genomes were sequenced using Sanger sequencing from two primary UM cell lines (92.1 and MEL270) and two cell lines (OMM2.3 and OMM2.5) derived from liver metastases of...

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Identifiers

PMID: 34082186
DOI: 10.1016/j.cancergen.2021.05.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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